First evidence of NEM’s chondroprotective effects published
This study, along with additional published studies, shows further substantiation for NEM supporting a healthy inflammatory response
Stratum Nutrition, in collaboration with the Traditional and Biomedical Research Center at Daejeon University and Ju Yeong NS Co., Ltd, is pleased to announce a new research study on NEM brand eggshell membrane has been published.
The study further validates NEM’s mechanism of action and reveals exciting insights on NEM’s ability to support joint health.
Researchers evaluated three doses of NEM (including the human equivalent dose of 52mg/kg) in a rat model of osteoarthritis. As in prior research, NEM again demonstrated powerful anti-inflammatory effects, in this case on the inflammation biomarkers Interleukin 1-beta (IL-1b) and C-Reactive Protein (CRP).
And, for the first time, chondroprotective effects were revealed from NEM treatment. NEM was found to reduce circulating cartilage degrading enzymes known as matrix metalloproteinases (MMPs) and was shown to reduce serum levels of the cartilage degradation biomarker CTX-II.
Importantly, the demonstrated chondroprotective effects were validated through histology, wherein a blinded pathologist evaluated cartilage thickness and joint space width both microscopically and via micro CT scan.
'The Korean researchers did a wonderful job of demonstrating the myriad benefits that NEM offers to arthritis sufferers. We are particularly excited about the chondroprotective effects shown with NEM and we have filed patent applications internationally surrounding this use for eggshell membrane,' commented Dr Kevin J. Ruff, Sr, Director of Scientific and Regulatory Affairs for Stratum Nutrition, which distributes NEM globally.
This study, along with additional published studies, shows further substantiation for NEM supporting a healthy inflammatory response.