Review evaluates fucoidan’s potential to mitigate lung damage

Published: 6-Jan-2021

Fucoidan is a highly bioactive compound that occurs naturally in brown seaweeds. It has been researched for anti-inflammatory, antioxidant, anti-tumorigenic and anti-viral effects

An Australian review has discussed recent research into the potential for the marine polysaccharide fucoidan to assist in limiting lung damage often caused by respiratory viral infections.

Respiratory viral infections, including COVID-19, can cause both acute and chronic damage to the lung. Chronic lung damage caused by respiratory viral infections, and ensuing bacterial infections, often takes considerable time to heal. It can also result in permanent lung scarring and difficulties in the rebuilding of damaged lung architecture.

The review summarises the current research on fucoidan and its potential to ameliorate viral lung infections and lung damage. It notes fucoidan has been shown to increase innate immunity and decrease inflammation in clinical and animal studies. Dietary fucoidan has been shown to attenuate pulmonary damage in an animal model of acute viral infection.

“The preservation of lung function and the limiting of lung damage may benefit individual patients and global health systems currently under immense strain,” said Marinova’s Chief Scientist and the lead author of the paper, Dr Helen Fitton. “Fucoidan preparations have potential as supplementary dietary agents to limit the damage caused by respiratory viral infections by restoring innate immune function and inhibiting inflammation. Marinova is continuing to explore this potential with additional studies investigating immune function.”

The paper: ‘Fucoidan and Lung Function: Value in Viral Infection’, published in Marine Drugs, can be accessed here.

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