Solv Wellness, a nutraceutical company focused on woman’s health, has released the results of a study suggesting that its cranberry extract can benefit those that suffer with UTIs more than D-mannose.
Urinary tract infections (UTIs) are generally triggered by the adherence of bacteria to the walls of the urinary tract, so if this can be prevented, the risk of developing such an infection is dramatically decreased.
Comparing cranberry extracts and D-mannose for UTI prevention
In this study — which is published in the Journal of Dietary Supplements — participants were either given Ellura, a 36mg proanthocyanidin standardised cranberry juice-based dietary supplement or D-mannose.
The study was conducted over a one-week period, and participants’ urine samples were collected throughout the trial period.
Urines were tested for bacterial anti-adhesion activity against P-type and Type 1 Escherichia coli, which are the two most common UTI-causing bacteria.
The results
From the one week trial period, results demonstrated that Ellura could effectively and consistently prevent the adhesion of both analogues of E. coli, but D-mannose’s anti-adhesion activity was inconsistent and limited.
This trend was particularly seen against P-type E. coli, which has often been found to cause serious kidney infections.
Researchers also hypothesised that the anti-adhesion activity seen in those who took D-mannose was not down to the supplement, but to an adhesion inhibitor the body naturally produces called Tamm-Horsfall protein.
These results cast doubt on the benefits of taking D-mannose for the maintenance of urinary tract health.
While supplementation with cranberry extracts and D-mannose are both commonly associated with UTI prevention, this study highlights the effectiveness of cranberry ingredients in reducing the risk of UTIs.
CEO of Solv Wellness, Teri Wade said: "Ellura's consistent performance against UTI-causing bacteria proves its unmatched efficacy. At Solv Wellness, our commitment to delivering science-backed solutions remains unwavering, and we are proud to showcase another successful study highlighting Ellura as the premier UTI supplement to help defend against UTIs.”
Ellura by Solv Wellness is backed by 21 clinical studies and 19 traditional medicine approvals worldwide.
