The randomised, double-blind, placebo-controlled study was done on 44 subjects over 12 weeks
BGG World (BGG) has announced a clinical trial has been successfully completed and published on a synergistic combination of TheraPrimE Palm Tocotrienols and AstaZine Natural Astaxanthin showing cognitive improvements in subjects with age-related memory decline.
The subjects were given a combination of 50mg of TheraPrimE Palm Tocotrienols and 9mg of AstaZine Natural Astaxanthin. Statistically significant results versus placebo were found using the Cognitrax cognitive test to measure composite memory domain as well as by subjective user evaluation.
Lead author Takahiro Sekikawa, PhD, commented, “We previously demonstrated that AstaZine Natural Astaxanthin alone was able to markedly ameliorate how well subjects can recognize, remember, and retrieve words and geometric figures. In this study we decided to add 50mg of tocotrienols to the same dosage of Astaxanthin previously tested and we were able to show a statistically significant amelioration versus the placebo group on Cognitrax in addition to improvement in all subjective symptoms measured.
"Previous research has established synergistic antioxidant performance of a Tocotrienol + Astaxanthin blend, and it would be of great interest to investigate in future studies if this outcome is due to an ameliorated absorption of Astaxanthin or perhaps to increased antioxidant activity due to the addition of tocotrienols.”