Layn Natural Ingredients, a functional ingredients manufacturer, has launched a polyphenol-rich botanical extract for better pet health.
TruGro CARE Joint Health can be used in pet food, treats and supplements, and aims to provide consumers with a comprehensive joint solution for their companion animals.
The functional ingredient contains a trio of polyphenol-rich extracts including:
- Epimedium: the source of the flavonoid Icarian, which has been proven to reduce bone respiration and promote osteoclast production to prevent bone loss 1,2
- Punicalagin: a phenolic compound found in pomegranate that inhibits the production of cytokines, which are involved in the inflammatory response
- Mangiferin: a mango leaf extract that acts as an antioxidant, while also inhibiting the metabolic processes that result in an inflammatory response
“Many products designed to promote joint integrity for our pet companions provide symptomatic relief by improving the range of motion or reducing discomfort,” said Layn’s Chief Scientific Officer, Jim Roza.
“However, these products contribute little to resolving the underlying causes of joint dysfunction. Causes such as inflammation, bone resorption, and cartilage loss are all contributory factors that can manifest into a loss of strength, motion, and quality of life. Our TruGro CARE Joint Health ingredient harnesses the power of polyphenols, demonstrated in numerous studies to inhibit oxidative stress, and thereby helping to address the root causes of joint discomfort and impairment.”
References
1 Effects of herbal Epimedium on the improvement of bone metabolic disorder through the induction of osteogenic differentiation from bone marrow-derived mesenchymal stem cells Mol Med Rep. 2017 Jan;15(1):125-130.
2 Icariin accelerates cartilage defect repair by promoting chondrogenic differentiation of BMSCs under conditions of oxygen-glucose deprivation J Cell Mol Med 2022 Jan;26(1):202-215