Karallief has announced the results of a clinical study that found its latest formula, Easy Climb, could be a fast-acting natural solution for joint discomfort. Published in the International Journal of Basic & Clinical Pharmacology, the study reportedly found the formula improved joint health and mobility in 30 days.
"Many supplement manufacturers, distributors and consumers are often sceptical about the effectiveness of herbal ingredients for joint support given the lack of clinically backed findings," said Krishna Rajendran, CEO of Karallief. "After extensive research and testing of different ingredients for joint health, our team of scientists discovered the synergy that exists when certain standardized herbal extract ingredients are combined in specific ratios. They subsequently developed a unique and effective multi-ingredient formula based on this synergy for supporting healthy joints, including cartilage, tendons and bones."
Easy Climb was tested over the course of 120 days in a randomised, double-blind, placebo-controlled clinical study on participants experiencing age-related knee concerns. One group of 40 participants received 1,000 mg of the Easy Climb formula each day, and a second group of 40 subjects served as the control and received a placebo. During the trial, the participants taking Easy Climb experienced a 71% decrease in discomfort scores compared to a 49% score for the placebo group and a 25% increase in joint space width compared 11% for the placebo group.
The Easy Climb cohort experienced an 8% improvement in the range of knee flexion compared to the placebo group value of 4%, in addition to a 16% increase in the number of sit-stand repetition versus the placebo group’s result of 8%.
The product is a herbal formula available in powdered form. This delivery method is aimed to provide flexibility to formulators, enabling it to be added to vitamins, supplements, protein powders, beverages and more. Its vegan, Non-GMO Project verified, and made with a 1,000 mg per day blend of standardised herbal ingredients known for supporting healthy joints including Cardiospermum halicacabum, Vitex Negundo, Boswellia Serrata, Bambusa Arundinacea, Citrus Sinensis and Curcuma Longa.