A study presented at the Experimental Biology Congress (Philadelphia, 2-5 April) concluded Bioiberica’s Dermial ingredient, a hyaluronic acid matrix ingredient for skin & beauty, delivers superior results for skin health over standard hyaluronic acid (HA), a popular ingredient in the nutricosmetic industry.
Comprising three naturally-occurring components, HA (60-75%), glycosaminoglycans, including dermatan and chondroitin sulfate, (≥10%) and collagen (≥5%), the ingredient reportedly offers anti-ageing, regenerative and moisturising properties to help maintain the health and nutrition of skin.
To determine the efficacy of Dermial versus standard HA (a widely studied molecule well-recognised for its anti-ageing benefits) the study explored its effects compared to standard HA from fermentation (HA-F) and extraction (HA-E) origins.
The in-vitro study found Dermial supplementation offered superior effects when compared to standard HA for inducing the synthesis of type I collagen, cell proliferation of HDF (human dermal fibroblasts) and cell migration of HEK (human epidermal keratinocytes).
This indicates the ingredient can bring regenerative activity to the dermis and epidermis layers of the skin, and support the maintenance and functionality of the dermis better than standard HA.
“These latest findings build on a growing bank of pre-clinical evidence highlighting the important benefits of Dermial for skin health,” said Daniel Martínez Puig, Head of R&D Human Health, Bioiberica. “Previous studies have revealed the ingredient’s mechanism of action, ability to be absorbed in the body and safety when taken orally. But now, we can also confirm that Dermial offers greater efficacy compared to standard HA.”
Jaume Reguant, Healthcare Director at Bioiberica said: “Dermial is a HA solution with a difference – helping manufacturers breathe new life into their innovation pipelines and create cutting-edge products that nourish, hydrate and replenish skin.”