The global demographic landscape is undergoing a profound transformation. According to the World Health Organization, the planet’s population is ageing rapidly and the number of people aged 60 years and older is projected to double by 2050 to reach 2.1 billion.

As populations live longer, the focus is shifting from extending our lifespan to enhancing our “healthspan.” This is the period of life spent in good health that’s free from chronic disease and disability.
This paradigm shift defines the burgeoning “age well” trend, a holistic approach to ageing that prioritises physical vitality, mental acuity and social engagement.
Individuals are no longer content with passive ageing; on the contrary, they want to actively take care of their “social ageing” by seeking ways to maintain their independence, pursue their passions and contribute meaningfully to society well into their later years.1
Today’s ageing population is more informed and proactive than previous generations. They view ageing not as a period of decline but as a phase of life to be optimised.
This mindset is driving demand for comprehensive solutions that support critical functions: physical mobility, cognitive sharpness, energy, immune resilience and emotional well-being.
Such a proactive approach fuels significant investment in personal health, with many exploring nutrition, exercise and supplementation to achieve their “age‑better” goals.
Healthy appearance: a visible reflection of internal vitality
Reflecting a holistic view of well-being, the pursuit of healthy ageing extends beyond internal vitality to encompass external appearance.
Vibrant skin and hair have become key indicators of overall vitality and a significant component of the age‑better trend.
Consumers increasingly recognise that a healthy look contributes to self-confidence, social engagement and an improved quality of life.
This growing awareness fuels a substantial global market; the antiageing segment was valued at $67.5 billion in 2023 and is projected to grow, demonstrating a collective commitment to maintaining a healthy and youthful aesthetic.2
Indena’s natural ingredients for a long, better-aged life
In this evolving landscape of health expectations, Indena stands out as a pioneering force by dedicating extensive research to understanding cellular ageing, optimising bodily functions and enhancing our appearance.
These three pillars are fundamental to achieving healthy longevity. Indena’s commitment is reflected in its portfolio of natural ingredients, which are meticulously validated with rigorous scientific studies.
CENTEXTRA® for skin health: firm, elastic, restored
The dermis, the skin’s deeper layer, serves as a critical interface by constantly signalling our internal health status to the outside world.
Exposed to a barrage of external stressors such as pollution and UV radiation, as well as internal factors such as anxiety and ageing, it requires robust support to maintain its integrity and youthful vitality.
Collagen, the body’s most abundant protein, is essential to provide structure, strength, firmness and elasticity to skin and other tissues.
However, the body’s natural collagen production begins to decrease as early as age 25, leading to thinner and more fragile skin, wrinkles and a loss of muscle tone.
To maintain healthy looking skin for longer, prompt action and the use of natural ingredients that reactivate endogenous collagen production is crucial to prevent long-term deterioration without adverse effects.
Centella asiatica L. offers numerous benefits for skin health. Its remarkable properties are attributed to unique triterpenoid acids and derivatives: madecassoside, asiaticoside, madecassic acid and asiatic acid.
These active compounds are scientifically proven to promote collagen synthesis, support wound healing, exhibit anti-inflammatory effects, provide antioxidant protection, stimulate microcirculation and help with water retention.
However, as with many powerful natural ingredients, the full potential of Centella is often limited by its inherently reduced bioabsorbability.
To unlock the full potential of its premium Centella extract while preserving its rich phytochemical profile, Indena has employed its proprietary delivery system, Indena Phytosome®, to ensure that its extract’s beneficial triterpenes remain intact and highly absorbable.
Rigorous preclinical tests demonstrate CENTEXTRA’s superior efficacy compared with an unformulated Centella extract. Its advantages include the following:
- enhanced antioxidant action: offers greater protection against reactive oxygen species (ROS), reducing oxidative stress risks
- support for a healthy inflammatory response: significantly lowers intracellular IL-6 release in response to inflammatory stimuli, promoting balanced inflammation
- superior cell migration: encourages wound healing and accelerates skin repair
- collagen level restoration: helps to restore collagen levels after oxidative stress and inhibits collagenase (MMP-1), which is vital to maintain skin integrity.
CENTEXTRA, the innovative Centella Indena Phytosome, stimulates collagen production and contributes to thicker, smoother and more radiant skin — truly promoting healthier and restored skin for longer.
It represents a significant advancement in the holistic management of skin ageing processes.
PUREBKALE®: purification, a foundation of health
Complementing its healthy appearance strategies, Indena offers PUREBKALE®, a food-grade extract designed to support the body’s detoxification processes and foster healthy looking skin.
With meticulous screening, Indena identified the optimal source of Brassica oleracea seeds to create an extract with a uniquely high glucoraphanin concentration (≥17%).
Produced exclusively with water as a solvent and leveraging a trusted Italian supply chain, PUREBKALE underscores Indena’s commitment to purity and quality.
Clinical studies have shown that PUREBKALE provides skin barrier integrity and dermal structure benefits, establishing it as a viable healthy ageing strategy for the skin.
Improvements were observed in firmness, elasticity, wrinkle depth and dermis density in women experiencing mild-to-moderate facial ageing signs.
PUREBKALE’s production demonstrates a strong commitment to sustainability by taking place in an ISO 14001 and ISO 45001-certified plant. Here, carbon dioxide emissions are reduced, energy transition initiatives are under way and occupational health/safety are prioritised.
Harnessing nature for a timeless quality of life
The age-better trend represents a fundamental and empowering shift in how society perceives and approaches ageing. It’s now an active pursuit of longevity, quality of life and sustained vitality across physical, cognitive, emotional and aesthetic dimensions.
As a recognised leader in the nutraceutical industry, with its unwavering focus on natural and scientifically validated solutions, Indena is uniquely positioned as a vital partner in this journey.
With innovative ingredients such as CENTEXTRA and PUREBKALE, Indena empowers individuals to actively pursue their goals of living longer, healthier and more fulfilling lives, profoundly demonstrating that nature offers effective solutions for a timeless quality of life.
The foundation of golden ageing begins today, naturally.

