Biotic supplement specialist resbiotic has launched the resM GLP-1 Postbiotic, a gut health solution that aims to support a consumer’s metabolic health and weight management efforts.
The formulation contains chromium picolinate, fenugreek, white mulberry leaf, rebiotic’s postbiotic L. Plantarum RSB11 and vitamin B12 — all of which work in synergy to stimulate the metabolism.
To find out more about the formulation, how biotic solutions are becoming the cornerstone of the weight management scene and the molecular mechanisms underlying the nutraceutical’s efficacy, NBR caught up with resbiotic’s founder and CEO, Dr Vivek Lal.
The time for metabolic health is now
The obesity crisis has impacted the lives of millions globally, and the negative consequences of this condition can span from metabolic syndromes to heart disease, cancer and an increased stroke risk.
It is estimated that 67 million Americans are obese, with more than half of this population requiring glucose support.
“The obesity epidemic has far-reaching consequences, so the physicians and scientists at resbiotic wanted to take a natural, targeted approach to combatting this issue,” comments Vivek.
“By leveraging drug development-level preclinical research, we developed a formulation with elements that can modulate blood sugar, reduce glucose spikes and promote a healthy metabolism.”
The resM GLP-1 Postbiotic contains a range of fit-for-purpose ingredients, including:
Chromium picolinate: Enhances insulin sensitivity, helping in the management of blood sugar levels
Fenugreek and white mulberry leaf: Two botanicals that can reduce post-meal glucose spikes, while supporting carbohydrate metabolism
L. Plantarum RSB11: resbiotic’s proprietary postbiotic that supports gut health — a crucial factor in metabolic wellness
Vitamin B12: A key contributor to the energy production process, reducing fatigue in users
“Postbiotics can support metabolic health and weight management by reducing inflammation, strengthening the gut barrier and improving insulin sensitivity,” adds Vivek.
“Short-chain fatty acids (SCFAs) such as butyrate, acetate and propionate are produced when probiotics ferment dietary fibre in the gut. SCFAs are grouped under the definition of ‘postbiotic’, and play a key role in regulating fat metabolism, supporting the function of insulin and reducing inflammation in the gut and beyond.
By promoting a balanced gut microbiome, postbiotics can enhance digestive health, which is essential for optimal metabolic function and weight management.
“There’s also emerging evidence that postbiotics may influence appetite-regulating hormones, potentially reducing hunger,” iterates Vivek.
“By promoting the release of GLP-1— a key hormone involved in satiety — resM GLP-1 postbiotic helps a user to feel more satisfied after meals and manage cravings.”
Is the gut the key to weight management?
The dysfunctioning of the gut microbiome has been linked to a plethora of chronic illnesses, and modern science has revealed that these bacteria can influence the immune system and the brain too.
“The gut-brain axis regulates hunger and satiety hormones like ghrelin and leptin — reducing overeating and unhealthy cravings,” comments Vivek. “Optimal gut health also influences how the body stores and utilises fat, promoting its breakdown and preventing excessive accumulation.”
By maintaining a diet rich in fibre, fermented foods and prebiotics, individuals can support their gut health and improve their weight management efforts.
Although there is a substantial amount of research backing the gut health-boosting activity of postbiotics, Vivek and the team at resbiotic are conducting a clinical trial on the resM GLP-1 Postbiotic to see its impacts in vivo.
“We currently have a randomised, placebo-controlled human clinical study in progress for the product. It’s designed to evaluate changes in weight, BMI and blood biomarkers relevant to metabolism.”
“We’re also looking into how the product impacts quality of life — particularly in relation to cravings. The study will span 1-2 months, providing important insights into the product’s benefits for metabolic health and overall well-being.”