How Vidya Herbs helps women’s health and well-being

During her life, first as a young girl and then as a woman, her body will undergo significant physiological changes that may be very uncomfortable. The first discomforts arrive with puberty, which stay with her throughout her entire life until the “great change of menopause.”

Dysmenorrhea, premenstrual syndrome, anxiety, sexual dysfunction, UTIs, menopause (and its manifestations) and osteoporosis may affect her entire life.

Dysmenorrhoea is a painful menstrual period caused by uterine contractions. It can induce severe and frequent menstrual cramps and usually lasts for life. Most women experience some symptoms a few days before their period. The most common symptoms of premenstrual syndrome are breast tenderness, changes in bowel habits, menstrual cramps and mood swings.

It is a given that, during a woman’s life, distinct periods of hormonal changes — such as puberty, premenstruation, pregnancy or postpartum (in some women) — and, of course, the menopausal transition, will cause her to experience anxiety. Many women experience sexual dysfunction such as an inability to achieve orgasm. In cases of sexual dysfunction, women may suffer from sexual arousal disorders, orgasm disorders or hypoactive sexual desire disorders.

Urinary tract infections (UTIs) are very common medical issues that affect the urinary tract of women. Among the several infections that affect women, UTIs are one of the most common bacterial infections. Symptoms typically include the need to urinate often, pain when urinating and discomfort in the side or the lower back.

Menopause is a natural biological process that happens to women in their 40s or 50s and marks the end of menstruation. In the months leading up to menopause, some typical symptoms or manifestations may appear, such as hot flushes, night sweats, sleep problems, mood changes, weight gain, thinning hair and dry skin.

The main health risk for women as they age is osteoporosis. This health condition results in bones that are weak, brittle and more likely to break. Osteoporosis is not usually painful until a bone is broken, but spinal fractures are a common cause of long-term pain. A selection of four traditional Ayurvedic ingredients and two specifically developed extract are presented.

Ashwagandha
Viwithan is a standardised form of withaferin A extract that is one of the withanolides responsible for the anxiolytic activity that may address the irritability and stress that occur during menopause.¹

Ashwagandha (Withania somnifera) also helps to alleviate menopausal symptoms as shown in a clinical trial when a statistically significant reduction in total Menopause Rating Scale and Menopause Specific Quality of Life scores were recorded.²

Ashwagandha can also help in the fight against osteoporosis; withaferin A (Viwithan) is involved in healing osteoporotic bones by stimulating bone formation, which has been confirmed in an animal model.^3,4

Regarding sexuality, a pilot study demonstrated that oral administration of an ashwagandha root extract can improve sexual function in healthy women.⁵

Shatavari
Shatavari (Apsaragus racemosus) contains saponins that maintain spontaneous uterine motility, which confirms its usefulness in dysmenorrhea, premenstrual syndrome and irregular bleeding during perimenopausal periods.⁶

A trial demonstrated that shatavari not only reduces urinary tract infections, it also boosts the immune mechanism of the body, thereby improving general health and preventing the recurrence of this infection.⁷ This plant is also known as a source of phytoestrogens that can be effective in reducing adverse menopausal symptoms.⁶

Chebulic myrobalan
Modern science has demonstrated the effect of chebulic myrobalan Terminalia chebula on E. coli and other urinary pathogens, including some that are resistant to allopathy. From this, it can be deduced that Terminalia chebula is of particular interest as a remedy for urinary tract infections and as an alternative to the well-known cranberry.⁸

Turmeric
Curcumin from turmeric (Curcuma longa) has been shown in a clinical trial to be effective in reducing the pain caused by dysmenorrhea.⁹ Curcumin may act by modulating the inflammatory response, which can reduce or even inhibit uterine contractions.¹⁰

Curcumin provides relief in premenstrual disorders as demonstrated in a clinical trial: a reduction in the total severity syndrome score was recorded.¹¹ It seems that curcumin is acting through neurotrophic effects.^12,13

It was concluded that curcumin was able to inhibit the biofilm formation of uropathogens, such as Escherichia coli, Pseudomonas aeruginosa, Proteus mirabilis and Serratia marcescens, possibly by interfering with their Quorum Sensing systems.¹⁴

Dealing with ageing, a triple-blind randomised controlled clinical trial was done with curcumin capsules and showed that the oral intake of curcumin significantly reduced hot flushes in postmenopausal women.¹⁵

SkinCera
Skin ageing is a significant concern for many women. SkinCera (Amorphophallus konjac), a ceramide-titrated konjac extract, showed improvement in dryness, age spots, redness, itching and oiliness, as well as more general antiageing properties in a pilot study.¹⁶

SUNCA
Maintaining a healthy weight is not just an issue for young women; it becomes particularly important during the menopause. Our studies have shown that Sunca (Helianthus annuus), a sunflower extract titrated with chlorogenic acids, is able to promote weight loss more specifically in women older than 30.¹⁷

Conclusion
With these ingredients inspired by traditional medicine and modern science, Vidya Herbs helps women make their daily lives more comfortable and healthier.

References

1. Z.A. Khan and A.R. Ghosh, “Withaferin-A Displays Enhanced Anxiolytic Efficacy without Tolerance in Rats Following Subchronic Administration,” African Journal of Biotechnology 10(60), 12973–12978 (2011).
2. S. Gopal, et al., “Effect of an Ashwagandha (Withania somnifera) Root Extract on Climacteric Symptoms in Women During Perimenopause: A Randomized, Double-Blind, Placebo-Controlled Study,” J. Obstet. Gynaecol. Res. 47(12), 4414–4425 (2021).
3. V. Khedgikar, et al., “Withaferin A: A Proteasomal Inhibitor Promotes Healing After Injury and Exerts Anabolic Effect on Osteoporotic Bone,” Cell Death and Disease 4, e778 (2013).
4. P.R. Nagareddy and M. Lakshmana, “Withania somnifera Improves Bone Calcification in Calcium Deficient Ovariectomized Rats,” J. Pharm. Pharmacol. 58(4), 513–519 (2006).
5. S. Dongre, D. Langade and S. Bhattacharyya, “Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract in Improving Sexual Function in Women: A Pilot Study,” Biomed. Res. Int. (2015): doi: 10.1155/2015/284154.
6. P. Shaha and A. Bellankimath, “Pharmacological Profile of Asparagus racemosus: A Review,” Int. J. Curr. Microbiol. App. Sci. 6(11), 1215–1223 (2017).
7. R.H. Arya, V.V. Shincymol and S.M. Oommen, “Clinical Trial on the Efficacy of Root Powder of Asparagus racemosus Willd. (Shatavari) in Urinary Tract Infection,” International Research Journal of Pharmacy and Medical Sciences (IRJPMS) 1(6), 53–57 (2018).
8. A. Bag, et al., “Evaluation of Antibacterial Properties of Chebulic Myrobalan (Fruit of Terminalia chebula Retz.) Extracts Against Methicillin Resistant Staphylococcus aureus and Trimethoprim-Sulphamethoxazole Resistant Uropathogenic Escherichia coli,” African Journal of Plant Science 3(2), 25–29 (2009).
9. N.S. Tabari, et al., “An Investigation of the Effect of Curcumin (Turmeric) Capsules on the Severity and Duration of Dysmenorrhea in Students of Iran University of Medical Sciences,” J. Evolution. Med. Dent. Sci. 9(46), 3444–3451 (2020).
10. R.B. Utami, D.F. Damayanti and D. Rodiah, “The Effectiveness of Curcuma longa Drink in Decreasing the Intensity of Dysmenorrhea,” Biomed. Pharmacol. J. 13(4), https://dx.doi.org/10.13005/bpj/2085 (2020).
11. S. Khayat, et al., “Curcumin Attenuates Severity of Premenstrual Syndrome Symptoms: A Randomized, Double-Blind, Placebo-Controlled Trial,” Complement. Ther. Med. 23(3), 318–324 (2015).
12. A. Cubeddu, et al., “Brain-Derived Neurotrophic Factor Plasma Variation During the Different Phases of the Menstrual Cycle in Women with Premenstrual Syndrome,” Psychoneuroendocrinology 36(4), 523–530 (2011).
13. H. Fanaei, et al., “Effect of Curcumin on Serum Brain-Derived Neurotrophic Factor Levels in Women with Premenstrual Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial,” Neuropeptides 56, 25–31 (2016).
14. I.A. Packiavathy, et al., “Inhibition of Biofilm Development of Uropathogens by Curcumin — An Anti-Quorum Sensing Agent from Curcuma longa,” Food Chem. 148, 453–460 (2014).
15. K. Ataei-Almanghadim, et al., “The Effect of Oral Capsule of Curcumin and Vitamin E on the Hot Flashes and Anxiety in Postmenopausal Women: A Triple Blind Randomised Controlled Trial,” Complement. Ther. Med. 48, 102267 (2020).
16. S.H. Venkataramana, N. Puttaswamy and S. Kodimule, “Potential Benefits of Oral Administration of Amorphophallus konjac Glycosylceramides on Skin Health — A Randomized Clinical Study,” BMC Complement. Med. Ther. 20(1), 26 (2020).
17. A. Leverrier, et al., “Helianthus annuus Seed Extract Affects Weight and Body Composition of Healthy Obese Adults During 12 Weeks of Consumption: A Randomized, Double-Blind, Placebo-Controlled Pilot Study,” Nutrients 11(5), 1080 (2019).