A new cancer nutritional intervention study has demonstrated the link between gut health and prostate cancer.
The research, published in the journal European Urology Oncology, is the largest, most comprehensive evaluation of nutritional interventions in prostate cancer to date.
It demonstrated that the phytochemical rich food blend, YourPhyto, not only significantly slowed PSA progression to a higher degree than previously reported, but also improved urinary symptoms and erectile function.
In addition, this was the world's first double blind RCT to show that a probiotic also further reduced PSA progression, improved markers of inflammation and grip strength (markers of overall health & longevity).
The trial provides essential scientific evidence for health professionals and practical guidance for people with cancer, interested in empowering themselves with the most effective strategies to improve their well-being and help alleviate the toxicities of hormonal, radiotherapy or surgical treatments.
Men who stopped all other supplements and took two capsules of YourgutPlus along with two capsules of YourPhyto a day showed the following improvements:
- A 44% slower rate of prostate cancer progression, measured by PSA levels,
- MRI scans of the disease showed stabilised disease or even disease shrinkage in 91% of participants,
- A 25% improvement in urinary symptoms,
- A 11% improvement in erectile function,
- Reduced blood markers of systemic inflammation,
- And enhanced grip strength as well as other markers of longevity.
Novel features of the new supplements made for these studies
YourPhyto contains pomegranate, broccoli, green tea and turmeric, which have all been shown to be beneficial in previous studies conducted by the same research team.
However, the supplement now includes new ingredients and embraces advances in food fortification, safety and technology.
These include purification, measurement and standardisation of the candidate phytochemical ensuring each capsule maintains its effectiveness and safety.
Traditionally supplements either have extracts of plants or dried whole plants — uniquely, this new supplement has both.
This ensures a wide spectrum of synergistically acting natural elements from the whole plant, but also boosts levels of the most active phytochemicals responsible for the health benefits.
During the last ten years, other foods have also demonstrated benefits in studies, particularly cranberry and organic ginger, both of which are included in these new capsules.
Cranberry reduced markers of disease progression and helped urinary urgency. Ginger aided digestion and improved gut health and is a known bio-enhancer, meaning it promotes the absorption of healthy phytochemicals.
Yourgutplus contains five non-histamine inducing, non-diary, lactose secreting lactobacillus bacterial strains, combined with inulin from chicory and vitamin D.
It has been previously evaluated and found to be beneficial in the UK national COVID nutritional intervention study and was chosen for the current covid vaccine support study, thus, has an excellent track record.
Rational for the study
Existing research shows that phytochemical intake and probiotics work in synergy to improve gut health and reduce inflammation in the body.
Laboratory studies have already shown that manipulating gut bacteria can slow prostate cancer progression but, until now, no clinical studies in men had investigated combining phytochemicals with probiotics.
As both these capsules were specifically made for national medical trials, the ethical committee insisted on a level of quality assurance unprecedented in supplement manufacturing.
In this double blind randomised clinical trial, men with early but progressive prostate cancer were given the opportunity to try these nutritional interventions before considering treatments such as surgery, radiotherapy or hormone therapies, which have significant risks and toxicities that impact quality of life.
None of the men in the study were taking any other supplements treatments for their prostate cancer.
In an unprecedented result for a nutritional trial, the MRI scans taken before and after the interventions supported the PSA findings. In the combined group, disease on MRI actually reduced in size in seven per cent of paricipants and stabilised in 84%.
Low grip strength (GS), along with inflammation levels is a practical biomarker for increasing age (longevity), the risk of chronic degenerative disease, including cancer.
In younger people — particularly athletes — phytochemical-rich foods and probiotics have independently been shown to improve strength and performance.
However, this is the first study showing a statistically significant effect of a nutritional intervention in an older population.
To conclude
YourPhyto is now the most up-to-date, comprehensively researched supplement available over the counter.
It’s scientific evaluation not only significantly slowed PSA progression to a higher degree than previously reported, but also improved urinary symptoms and erectile function.
This is the world's first double blind RCT to demonstrate that a probiotic intervention, Yourgutplus further reduced PSA progression, reduced longevity markers of inflammation and improved grip strength.
This combination has been choice for a major intervention study in women and further trials are planned evaluating their role for enhancing sports performance, strength and longevity.