Gnosis by Lesaffre Gnosis by Lesaffre

Via Lavoratori Autobianchi 1
Desio (MB)

+39 0362 16 70 001



Gnosis by Lesaffre, a business unit of Lesaffre, is a world expert in yeast, bacteria and pure molecule from fermentation, dedicated to human health and nutrition.


Gnosis by Lesaffre

Microorganisms are invisible agents of change, facilitating our mobility, protecting us from disease, and helping us adapt to our ever-changing environment. At Gnosis by Lesaffre, microorganisms are a part of our workforce.

We harness their power and biotransformation processes like fermentation to cultivate nutritional actives, probiotics, and nutritional and functional yeasts that benefit human health and wellbeing. We strive to create a world that moves better, digests better, ages better, feels better, and, ultimately, lives better thanks to microorganisms and biotransformation.

We draw on our focused research and development capabilities, rigorous quality and regulatory standards, and extensive clinical validation procedures so that we can develop effective solutions for the Wellness and Immune Health, Digestion & Gut Health, Mobility & Joint Health, Reproduction & Women’s Health, and Mood & Cognitive Health markets. Our processes are replicable, reliable, and meticulously studied, so that we can maintain unrivaled quality and consistency while scaling up production.

We collaborate with nutraceutical and pharmaceutical brands to develop game-changing products that help their customers thrive. We’re true partners to our customers, supporting them with a portfolio of branded solutions, scientific guidance, clinical studies, and more.

We relentlessly explore the potential of microbial biotransformation–an untapped, transformative resource–to develop natural, sustainable, and efficacious solutions. At Gnosis, we use what’s alive so that we and our planet can thrive.

Product lines

Quatrefolic® is the glucosamine salt of (6S)-5-methyltetrahydrofolate and is structurally analogous to the reduced and active form of folic acid. It provides greater stability, higher water solubility and multiple ingredients formulation flexibility compared to 5-methyltetrahydrofolate calcium salt.

Ibsium® is an exclusive live healthy yeast strain (saccharomyces cerevisiae CNCM I-3856) patented by Lesaffre and designed to support intestinal comfort. Its effectiveness has been demonstrated on more than 1700 volunteers including 600 during clinical studies.

VitaMK7® is the active isomer of natural Vitamin K2 with the highest bioavailability and longest half-life in the blood. K2&Olive™ combines nutritional beneficial properties of extra virgin olive oil and benefits of Menaquinone-7.

Quatreflora™ - Unique patented healthy yeast to support healthy balance of vaginal microflora. Discover the science behind it with peer-reviewed publications demonstrating its clinical efficacy and beneficial effects.

Mythocondro® is the first Non-Animal Chondroitin Sulfate produced by a patented fermentation-based manufacturing process.

Lynside® ProteYn - The World’s population is projected to grow to 9.7 billion people by 2050, that’s why the need for sustainable, affordable and healthy protein sources is on the rise. SSE is the occasion for Gnosis by Lesaffre to feature Lynside® ProteYn, the alternative and complete source of protein from yeast. Containing all essential amino acids, including branched-chain amino acids, Lynside® ProteYn is a complete source of protein, perfect for people looking at enhancing their protein intake with non-animal protein sources.

Adonat® is the commercially stable form of S-Adenosyl-L-methionine (SAMe) and it has been shown to have mood enhancing, hepatoprotective and pro-joint activities. Adomet® is produced from a selected proprietary highly productive yeast using fermentation technologies which generate a superior quality of the ingredient.

LifeinU™ L.rhamnosus GG is lactobacillus rhamnosus GG is one of the most studied probiotic bacterium and it has shown beneficial effects on both digestive and immune health.

Emothion™ is S-Acetyl Glutathione, an alternative form of the reduced GSH. Several studies have shown that this precursor of GSH is well-absorbed and more stable throughout the digestive tract than the L- glutathione reduced and has a positive effect on many oxidative stress biomarkers.

Lynside® Nutri is a range of non-fortified yeasts rich in protein, fiber, vitamins and minerals.

Biootic® is a probiotic yeast (Saccharomyces boulardii) acting as a temporary flora to protect intestinal tract and good germs in the intestine.

Phosphocomplex® is obtained from the complexation of Silybin with phospholipids. Silybin is the primary active flavonolignan in Silymarin extract (milk thistle plant) used so far as hepatoprotectants

Adomix®, is the SAMe stabilized powder for fast drug absorption and extensive formulation possibilities in capsule dosage.

Adogran®, is a formulated bulk powder consisting of coated granules containing SAMe.

SamEspresso® is the mouth soluble granulate with improved stability and fast SAMe release.

SupereSSe® is the dried yeast (Saccharomyces cerevisiae) with a high content of the enzymatically active active form (S,S) Adenosyl-methionine.

Adonat Tablets® Conventional enteric-coated tablets in different dosages and combinations for direct release of the ingredient in the intestine, good absorption and tolerability.

Soloesse®, are All Natural Tables offering the absence of synthetic derivatives for consumers, asking for all- natural ingredients.

SAMe Drink® is a mouth-soluble granulate, alternative for people who cannot swallow or who dislike swallow coated tablets.

Additional contact:

137 rue Gabriel Péri

59700 Marcq-en-Baroeul – France

+33 (0)3 20 81 61 00


For US enquiries:

Gnosis USA Inc.

4259 West Swamp Road

3rd Floor Suite 305

Doylestown, Pennsylvania

18902 - USA




Quatrefolic; Ibsium; VitaMK7; Quatreflora; Mythocondro; Lynside ProteYn; Adonat; LifeinU; Emothion; Lynside Nutri; Biootic; Phosphocomplex; Adomix; Adogran; SamEspresso; SupereSSe; Soloesse; SAMe Drink; Adonat Tablets;