Clinical study finds microalgae extract BrainPhyt may boost cognitive function in older adults

Published: 3-Oct-2024

New research published in the peer-reviewed journal Nutrients demonstrates that BrainPhyt, a natural microalgae ingredient featuring a unique and patented composition of bioactives, significantly enhances cognitive function in older adults experiencing memory decline

Developed by Microphyt, BrainPhyt is derived from the microalgae Phaeodactylum tricornutum Mi136.M1.a and shows promising results in supporting brain health.

The double-blind, randomised, placebo-controlled study involved 43 healthy, physically active adults aged 55 to 75 who reported experiencing memory and cognitive decline.

During a 12-week period, participants received either BrainPhyt in its powder form at a daily dose of 1100 mg (providing 8.8 mg of fucoxanthin) or a placebo.

To measure the effects, cognitive assessments and blood samples were collected at the start,and after 4 and 12 weeks to evaluate the effects of supplementation.

In addition to assessing various cognitive parameters, such as executive function, attention, and short- and long-term memory, the study also measured stress levels, mood, sleep quality and any potential side effects.

The results support BrainPhyt’s promising potential for enhancing cognitive function in healthy, older adults, as well as support for overall cognitive wellness.

  • Enhanced cognitive function: Participants showed significant improvements in working and episodic memory, reaction times, attention, vigilance, and executive function following supplementation with BrainPhyt.
  • Improved insulin sensitivity: BrainPhyt supplementation increased insulin sensitivity, which has been associated with maintaining cognitive health and preventing neurodegenerative diseases.
  • Better sleep quality: Participants reported significant improvements in sleep, including increased calmness, ease of awakening, and better alertness upon waking. This positive impact on sleep could contribute to BrainPhyt’s benefits for cognitive function.
  • No adverse side-effects: The study found no negative effects on clinical blood markers, underscoring BrainPhyt’s strong safety profile.  BrainPhyt is recognized as safe according to the New Dietary Ingredient (NDI) notification number 1120, granted by the US Food and Drug Administration (FDA) in 2019.

The unique and patented composition of BrainPhyt features fucoxanthin, a marine carotenoid, along with omega-3 fatty acids such as EPA and certain sterols, making it a promising natural supplement ingredient for cognitive health.

“As fucoxanthin crosses the blood-brain barrier and appears to support cognitive function through a combination of mechanisms,” explained Dr Jonathan Maury, PhD, Clinical Research Manager of Microphyt.

“Based on existing literature, its benefits include antioxidant and anti-inflammatory effects, enhanced insulin sensitivity, support of neuronal health and synaptic plasticity, reduction of perceived stress, and improved sleep quality.”

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“These findings suggest that BrainPhyt supplementation may play a role in mitigating early signs of cognitive decline in healthy older individuals,” added Professor Richard Kreider, PhD, Department of Kinesiology and Sports Management, Texas A&M University, and a study researcher.

“This research contributes to the growing body of evidence that nutritional interventions can support brain health and cognitive function as we age.”
 

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