Botanic Healthcare reports clinical results for IRONNOX in iron-deficiency anaemia study

Liposomal iron ingredient demonstrates improvements in key iron-status markers and gastrointestinal tolerability

In a randomised, active-controlled, 56-day clinical study involving 60 women with iron-deficiency anaemia, IRONNOX® demonstrated greater improvements in key iron-status parameters compared with conventional ferric pyrophosphate. By Day 56, haemoglobin levels were 7.2% higher, while serum ferritin was 41.8% higher in the IRONNOX® group. Transferrin saturation was also 18.8% higher, alongside an 18% lower fatigue score.

Notably, no gastrointestinal-related adverse events were reported in the IRONNOX® group, compared with 20% in the conventional ferric pyrophosphate group.

"Iron supplementation should not be a compromise between efficacy and tolerability. Our clinical findings with IRONNOX® demonstrate the potential of advanced delivery technology to improve key markers of iron status while maintaining favourable gastrointestinal tolerability," said Gaurav Soni, Managing Director, Botanic Healthcare.

Madhu Krishnamani, Managing Director, Botanic Healthcare, added: "These results strengthen our commitment to developing clinically researched nutritional ingredients that address important challenges in iron supplementation."

Dr Shiv, Chief Scientific Officer, Botanic Healthcare, said: "The clinical findings demonstrate improvements across key markers of iron status, supporting the potential of liposomal delivery for iron supplementation. The study, led by Dr Sravani and the clinical research team, provided important evidence supporting the performance of liposomal ferric pyrophosphate. Our Caco-2 permeability data demonstrated 2.1-fold higher permeability for liposomal ferric pyrophosphate compared with conventional ferric pyrophosphate, providing additional in vitro supporting evidence for the liposomal delivery approach."

The findings add to Botanic Healthcare's growing focus on clinically researched delivery technologies designed to support the performance and user experience of nutritional ingredients.

You may also like