AFYREN and South Africa-based Esse Skincare are partnering to introduce the world’s first bio-based propionic acid for the skincare industry.
Propionic acid is a naturally occurring short-chain fatty acid essential for maintaining a balanced skin microbiome.
Emerging research suggests it helps modulate inflammation, support barrier resilience and maintain microbial balance — key to hydrated, resilient skin.
Until now, propionic acid has only been available at an industrial scale from petrochemical sources.
Through this partnership, Esse gains access to AFYREN’s sustainably produced, COSMOS-certified, bio-based alternative propionic acid made at AFYREN NEOXY, the company’s flagship industrial biorefinery.
Using AFYREN’s proprietary circular, low-carbon fermentation process, the plant is the first in the world capable of producing a portfolio of organic acids at a commercial scale.
"Our collaboration with AFYREN allows us to use a natural microbial metabolite in its pure, bio-based form — a first for the skincare industry,” said the late Trevor Steyn, founder of Esse.
"This agreement represents a significant step toward creating formulations that work in harmony with the skin’s natural ecosystem, opening the door to new cosmetic solutions that stay true to this principle."
Nicolas Sordet, CEO of Afyren, added: "This shows how biotechnology can unlock new opportunities for both performance and sustainability in cosmetics that bring real benefits to humans and the environment."
"We look forward to seeing the first products reach consumers."
Together, Esse and Afyren are shaping a new generation of skincare products — one that merges biotechnology, sustainability and proven skin science.
Those interested in evidence-based skincare will find the Anti-Ageing Skin Care Conference a valuable resource, bringing together researchers, dermatologists and product developers across the sector. Find out more HERE.