Solabia Nutrition and RUMC delve into the signalling behind skin health

Published: 14-Jun-2024

The project will aim to enhance the clinical understanding of how botanical ingredients can impact skin homeostasis and keratocyte signalling

Solabia Nutrition, a nutraceutical ingredients specialist and the Radboud University Medical Center (RUMC) have begun collaborations to support the Dermaphenolics project.

The idea behind the initiative is to enhance the clinical understanding of cellular signalling linked to skin health, and will use Solabia’s pipeline of leads.

Solabia Nutrition has significant experience in the development of active botanical ingredients — mainly focusing on women’s health, cognitive function, healthy aging and the gut-skin axis.

RUMC is affiliated with Radboud University in the Netherlands, and is an institution focused on dermatology, both in the contexts of patient care and research. 

What the study entails

The project will study the effect of phenolics on in-vitro skin cell cultures, focusing on keratinocyte cellular signalling and skin homeostasis.

These phenolic compounds are currently being studied by Solabia Nutrition in clinical studies for various applications — including their ability to modulate skin physiology.

Solabia Nutrition’s head of R&D Yala Stevens takes the lead in this collaboration together with Prof. Ellen van den Bogaard, the head of the Laboratory for Experimental Dermatology at RUMC.

Yala Stevens comments: “This is a great first step in understanding the impact that our phenolic lead compounds could have on skin cells and skin homeostasis. The Dermophenolics Project will allow us to get mechanistic insights in the area of skin biology and be the basis for further clinical validation.”

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