PycnoCentella: a new research-based combination ingredient for atherosclerosis (part I)

Published: 2-Oct-2025

A novel combination of Pycnogenol and Centellicum has been shown to prevent the progression, improve the stability and reduce the number and size of atherosclerotic plaques, thereby supporting cardiovascular health with its anti-inflammatory and antioxidant properties

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Atherosclerosis is a chronic disease in which cholesterol, fats and other substances (such as calcium) deposit on the inner wall of arterial blood vessels.1

This buildup of substances on the artery wall is called plaque. With time, arterial plaque can progressively stiffen and clog arteries.

That process can cause arteries to narrow, which leads to a reduced supply of blood and nutrients to body tissues.

In the worst case, the plaque can burst, leading to the release of a blood clot that, in turn, can trigger serious problems such as stroke, heart attack or thrombosis.

Dr Franziska Weichmann, Manager of Scientific Communications and Product Development, Horphag Research, reports. 

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