Supplementation with botanicals and other natural extracts has been a concept for millennia, with many ancient Ayurvedic ingredients such as ashwagandha and curcumin remaining popular in modern formulations. Although dietary supplements and nutraceutical products
have come a long way since the early tinctures produced by our ancestors, certain ingredients still pose manufacturing challenges — mostly owing to their solubility, stability, bioavailability and sensitivity to processing.
To overcome these hurdles, formulators in the nutraceutical space are now using ways to deliver supplement ingredients more effectively by focusing on everything from encapsulation to long-release, ingredient stabilisation and excipient optimisation. These methods are all highly familiar to manufacturers of pharmaceutical oral solid dosage forms who routinely seek out and develop technologies to optimise the delivery of active ingredients.
These concepts become particularly important when creating products designed as sleep aids, adaptogenic stress managers or energy boosters; these formulations require the controlled long-term release of bioactives to ensure that the product has the intended effect
at the right time. To discover how brands can effectively optimise the delivery of their natural ingredients, why it’s important to do so and key considerations when creating specialist, user-friendly supplements, NBR caught up with Dr Nima Alamdari, Chief Scientific Officer of
Ritual.