The symbiotic relationship between phenolic compounds and gut microbiota have gained attention due to their relevance in supporting human health, specifically in their role for gut & digestive support as well as skin health and beauty from within. In particular, pomegranate has long been associated with possessing high content antioxidant polyphenols, in particular ellagitannins such as punicalagins and their gut-derived metabolites, urolithins.
Overall, findings from pre-clinical and human clinical studies support pomegranate ellagitannins, namely punicalagins, can:
- exert prebiotic effects to enhance the growth of beneficial bacteria;
- alleviate gut microbial imbalance induced conditions;
- promote gut/digestive health by mediating the balance of pro- and anti-inflammatory status;
- offer skin health support through a balanced skin-gut microbiome;
- promote supple skin through collagen and elastin maintenance & AGE inhibition;
- support dermal and skin appearance from within.
Taken together, Pomella’s polyphenols and gut microbial metabolites contribute immensely to the health benefits associated with skin-gut axis. Consequently, Pomella®, a patented pomegranate fruit extract standardized to deliver bioactive phytochemicals including punicalagins, is a promising solution supporting gut and digestive health, skin health, and beauty from within.