The study was conducted in partnership with MoreBetter, a real-world data and research platform.
The study tracked the daily experiences of real users for 21 days and revealed statistically significant improvements in energy, focus and productivity without the use of caffeine or stimulants.
Scientifically measured, naturally effective
The RWE study provided consistent daily feedback on the Energy + Focus supplement, a proprietary formula that resulted in measurable and meaningful outcomes:
- 25% increase in daily energy
- 66% reported improved productivity
- 63% experienced reduced fatigue
- 61% noted better focus.
“This study exemplifies how real-world evidence can transform anecdotal usage into actionable science,” said Steve Curtis, CEO of VIVAZEN.
“Botanicals have played a critical role in traditional health practices for centuries, but research like this is essential to bring credibility and scientific rigour to the future of functional wellness.”
Why this research matters
In July 2025, the US FDA announced plans to schedule 7-hydroxymitragynine (7-OH), a potent synthetic derivative of kratom, as a Schedule I controlled substance, citing its opioid-like risks and safety data.
Crucially, regulators emphasised that natural kratom leaf products are not the target of this action.
Amid growing concern over adulterated products, this study offers timely, real-world data to distinguish authentic botanical formulas from dangerous synthetics and reinforces the need for science-based evaluation of kratom in everyday use.
Advancing wellness through research and transparency
To help advance public understanding and transparency, VIVAZEN partnered with the Network of Applied Pharmacognosy (NAP), a non-profit dedicated to accelerating research and education around natural medicines by centring lived experience and community engagement.
In alignment with this mission, NAP has published a summary of the study findings on its public platform, making the results more accessible to researchers, educators and everyday consumers alike.
Help shape the future of botanical science
This RWE study highlights a broader movement to validate natural products through real-world data, offering consumers and health care providers a clearer understanding of product efficacy outside of a lab environment.
As consumers increasingly seek non-synthetic, plant-based alternatives, real-world studies provide critical insights that help build trust, transparency and scientific credibility.