ButyraGen: new clinical study confirms digestive relief, with promising benefits for women

Published: 26-Jun-2025

Research-backed tributyrin complex shows significant results for post-menopausal women with GI discomfort

As gut health continues to be top of mind for wellness consumers, NutriScience Innovations’ ButyraGen® is showing new promise for individuals seeking effective, research-backed digestive support. Recent results from a large-scale, real-world setting clinical study underscore how this novel direct butyrate generator may provide meaningful relief for a range of digestive complaints, especially for women and post-menopausal women who often experience unique GI challenges.

Butyrate, a short-chain fatty acid, is well documented for its role in nourishing colon cells, supporting the gut barrier, and maintaining a healthy microbiome. However, achieving sufficient butyrate levels through diet alone can be difficult, particularly for those with poor fiber intake or a disrupted microbiome. ButyraGen® addresses this gap by providing a convenient, odor-free, powdered tributyrin complex that generates butyrate directly in the gut, regardless of the state of your microbiome.

ButyraGen: new clinical study confirms digestive relief, with promising benefits for women

In the recently published six-week, randomized, double-blind, placebo-controlled study involving nearly 600 adults across the U.S., 200 mg of ButyraGen® supplementation led to a statistically significant reduction in belly pain compared to placebo. Notably, the benefits were strongest among women, and even more so for post-menopausal women, a group that often faces heightened digestive discomfort due to hormonal changes and shifts in microbiome balance.

Beyond belly pain, the study highlighted support for both upper and lower GI issues, including gas, bloating, reflux, and mild constipation. Participants who began the study with mild reflux or constipation experienced significant quality of life improvements in as little as one week, suggesting ButyraGen® may help address the everyday GI discomforts that can take both a mental and physical toll on our wellbeing.

These findings highlight ButyraGen® as a compelling solution for anyone managing gut sensitivity or wanting to maintain digestive comfort, especially women navigating hormonal transitions. With its proven tolerability and an easy-to-use clinically studied dosage of 200 mg, ButyraGen® is an easy and effective addition to daily wellness routines, without the unpleasant odor or high doses often associated with other butyrate sources or fibers.

ButyraGen: new clinical study confirms digestive relief, with promising benefits for women

NutriScience Innovations remains committed to advancing science-backed gut health solutions that meet the needs of diverse consumer groups, including women who are frequently underrepresented in digestive health research.

For more information contact Sales@NutriScienceUSA.com | www.NutriScienceUSA.com

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