Prostatic ailments are among the most common urologic problems in adult males. BPH (benign prostatic hyperplasia) is the third most frequent urologic diagnosis in men over 50. Prostatitis can also affect young people, especially sportsmen and cyclists. Prostatic ailments share inflammation and oxidative stress as risk factors and cause of chronicity.
Epilobium angustifolium L. (Onagraceae) is a well-known European plant traditionally used for prostatic ailments and micturition disorders.
Enotprost by EPO s.r.l is a dry extract with a very rich phytocomplex containing more than 15% of Oenothein B. It is a strong anti-inflammatory and antioxidant ingredient for innovative prostate food supplements.
Oenothein B properties
Oenothein B has immunomodulatory, antioxidant and anti-inflammatory properties; the combined enhancement of innate immune defences and protection of host tissues through antioxidant effects could allow Oenothein B to optimally provide health benefits.
Thanks to the collaboration with the University of Pavia, EPO Srl carried out a preliminary study to assess bio accessibility and bioactivity (anti-inflammatory and antioxidant) using aerial parts of the plant (“herba”), collected in eastern Europe at springtime and then dried. The botanical species is certified by DNA barcoding analysis.
In vitrotests demonstrated that pre-treatment of prostatic cells with ENOTprost followed by LPS-induced inflammation, strongly reduces TNF-αα production. TNF-α α is one of the most important pro-inflammatory cytochines.
In vitro test demonstrated that treatment of prostatic cells with ENOTprost enhances cellular antioxidant defenses by increasing the level of SOD1. This enzyme is one of the most important endogenous antioxidant defense mechanisms.
Applications
Thanks to its properties Enotprost by EPO s.r.l can be used in the formulation of food supplements for seniors, sport food supplements and functional foods (bars).
The recommended intake is 300-400 mg dose 1-2 times daily.
Enotprost by EPO s.r.l is distributed in the US market and in Spain by Faravelli.
